Arthi Agarwal was born on 5th March in U.S.A., New Jersy. At the age of 14 years she got a chance to act in the movie with Sunil Shetty. She has a sister Adithi Agarwal, who was acted in the move Gangotri with Allu Arjun. Arthi Agarwal has the reputation for Tollywod's lucky mascon as all her movies played well.

Aarthi Agarwal made her acting debut in Bollywood with Paagalpan in the year 2001, which was unnoticed. She got an offer in the Telugu fillm Nuvvu Kaku Nachavu in the year 2001, directed by K.Vijaya Bhaskar. It was did well in the box office. After that she got many opportunites with leading actors.